It was a reversal of fortune for Barcelona who last term pulled off the greatest comeback in Champions League history by overcoming a 4-0 loss to Paris St Germain, becoming only the second team after Deportivo La Coruna in 2004 to progress after losing the first leg by at least a three-goal deficit.
Luis Suarez, Samuel Umtiti, Nelson Semedo and Jordi Alba looked like they were in Rome to sightsee, while only Marc-Andre ter Stegen and Lionel Messi salvaged their reputations.
Roma came back alive Tuesday night to knocked Barcelona out of the Champions League after a miracle comeback.
Barca slumped out at the quarter-final stage for the third year in a row after being eliminated by Juventus last season and Atletico Madrid in 2016.
Roma forward Edin Dzeko opened the scoring when he beat the offside trap and latched onto a perfectly weighted through ball from Daniele De Rossi to score in the sixth minute, lifting the hopes of the boisterous home fans in the Olympic Stadium.
Kostas Manolas headed the decisive third goal in the 82nd minute, putting the Italians in the semi-finals for the first time since they reached the European Cup final in 1984 and compensating for his own goal in the first leg at the Nou Camp.
The incredible 3-0 victory at the Stadio Olimpico saw the home side overhaul a 4-1 first-leg defeat and advance on away goals. “Rome’s historic feat: 3-0 against Barca, flying into the semi-finals. Messi and companions KO,” said Italian daily La Stampa, referencing the Spanish champions’ star forward.